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There are 155 sixteen-letter words containing 2E, 2N, 2S and Y

adenylosuccinaseannual␣ryegrassesanticyclogenesesanticyclogenesisantihypertensorsantihypotensivesantirecessionaryany␣other␣businessautogeosynclinesBayesian␣networksbloodyhandedness bloody-handednessbloodymindedness bloody-mindednessboundarylessnessbusiness-friendlyByzantine␣studieschanges␣of␣sceneryconsciencelesslyconsensus␣realitycontention␣systemcontinuity␣seriesconverse␣antonymsCopernican␣systemcynanversicosidedefense␣attorneysdemyelinisationsdental␣hygienistsdesaminotyrosinedestroying␣angelsdesynchronisableDomain␣Name␣Systemeastern␣poison␣ivyebony␣spleenwortsEgyptian␣darknesseleemosynarinessendocrine␣systemserysenegalenseinEurasian␣wrynecksfancy␣one's␣chancesfarnesylcysteinefeasting␣one's␣eyesFontenay-aux-Rosesfry␣someone's␣baconGardner's␣syndromegay␣panic␣defensesGenovese␣syndromeget␣someone's␣nannygreen␣lynx␣spidersgunnery␣sergeantsHelsinki␣syndromeHennebique␣systemheterosynkaryonshyperinstrumentshyperintensitieshypersensitisinghypersensitizinghypersynchroniesidentitylessnessImpeyan␣pheasantsinner␣Solar␣Systemis␣on␣one's␣merry␣wayisoselenocyanatekeep␣one's␣eyes␣openkept␣one's␣eyes␣openknit␣one's␣eyebrowslaying␣one's␣eyes␣onLobstein␣syndromeLos␣Angeles␣Countylumazine␣synthaselymphoneogenesismanagement␣systemmechanosynthesisMénière's␣syndromemethylguanosinesmethylmannosidesmethylserotoninsmoney␣of␣necessityNessler␣cylindersninetysomethings ninety-somethingsnonemphysematousnonheterocystousnonprogressivelynonsense␣syndromeoffensensitivityopen␣someone's␣eyesoversynthesizingparageosynclinespersonal␣hygienesphenylsuccinatesphosphanylidenespseudonymousnesspyomelanogenesisquintessentiallyRensselaer␣Countyresonance␣hybridsSaint␣Stephen's␣DaySandifer␣syndromesecondary␣accentssecondary␣modernssecondary␣planetssedimentary␣basinSelection␣MondaysSelection␣Sundaysselenomethionylsselfconsistentlyself-synchronizedself-synchronizessemantic␣analysessemisynchronizedsemisynthesizingsemitransparencyserpentinophytesseventysomething seventy-somethingSjögren's␣syndromesloppy-mindednessSneddon's␣syndromesnub-nosed␣monkeysspermostrychninesphingomyelinasespin-density␣wavesstands␣on␣ceremonystayed␣in␣one's␣lanesteady-handednessStendhal␣syndromeStephenson␣Countystone␣man␣syndromestonyheartedness stony-heartednessstrong␣silent␣typestrychnosperminesuperencryptionssurrender␣monkeyssweet␣young␣thingssynaptoneurosomesynchronous␣speedsynchrosqueezingsynsedimentarilysyntergosternitetransesterifyingtransfer␣paymentstranshydrogenasetreeman␣syndromestwentysomethings twenty-somethingsundersensitivityunemployablenessunmysteriousnessWestbury-on-Severnwestern␣poison␣ivywith␣one's␣eyes␣openYankee␣tunesmithsYour␣Highnessness

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