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There are 53 sixteen-letter words containing 2E, 2P, S and 2U

chuck␣up␣the␣spongecolour␣supplementcountersupportedCyprus␣turpentinehyperpseudopilusimmunosuppresiveimmunosuppressedimmunosuppressesimpulse␣purchasesmultiple-exposure multiple␣exposuremultipurposenessnecrosuppurativeneurosuppressionneurosuppressiveoverpopulousnessoverpresumptuousPapua␣New␣Guineanspeanut-butter␣cups peanut␣butter␣cupsperpetual␣curatesporcupine␣pufferspresumptuousnesspseudepigraphouspseudoepipleuralpseudoepipleuronpseudoleukopeniapseudo-penannularpseudopseudogoutpseudothelphusidPuestow␣procedurepurpureagitosidepush␣up␣the␣daisiesput␣up␣the␣shuttersseptum␣pellucidumsubperpendicularsupermastergroupsuperpermutationsuperprestigioussuperspectacularsupersulphuretedsupersuperlative super-superlativesupersuppressionsupersusceptiblesupertherapeuticsupratherapeuticsurge␣suppressorssurprise␣surpriseunprosperousnessunpurposefulnessunsupportivenessupper␣ten␣thousand

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See this list for:

  • Scrabble in English: no word
  • French Wiktionary: 107 words
  • Spanish Wiktionary: 7 words
  • Italian Wiktionary: no word
  • German Wiktionary: 49 words
  • Portuguese Wiktionary: 1 word
  • Dutch Wiktionary: 11 words

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