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There are 84 sixteen-letter words containing E, I, 2M and 3S

antisymmetrisersasymmetricalnessaxiomatic␣systemschemosystematicsChinese␣mushroomsChristmas␣marketscommission␣agentscommissionairesscommissioneratescommissionershipcommissionnairescommissurotomiescompression␣pumpsconsummativenesscrash␣test␣dummiesdecommissioningsdisembarrassmentdynamical␣systemsestablishmentismestemmenosuchidsfideicommissionsgenome␣assembliesimmeasurablenessimmensurablenessimmunosuppressedimmunosuppressesimmunosuppressorimmunosupressantimmunosupressionimmunosupressiveimpermissivenessimpossible␣dreamsincommodiousnessinstrumentalismsJames's␣flamingoeslymphatic␣systemsmarket␣socialismsMartinmas␣summersmeritorious␣mastsMesoamericanistsmessiah␣complexesmetal␣homeostasismetastasectomiesmetempsychosistsmetempsychosizesmicroanastomosesmicrobusinessmanmicrobusinessmenmicrocompressorsmicroseismogramsmidsummer␣daisiesmidsummer␣madnessmisappraisementsmissense␣mutationmission␣statementneoimpressionism neo-impressionismpluries␣summonsespromises,␣promisespseudosymmetriesroeslerstammiidssame-sex␣marriagesscreaming␣orgasmssemicolonialismssemi-postal␣stampssemisubmersiblessilvery␣marmosetssimplemindedness simple-mindednessSimple␣Simon␣oversSix's␣thermometersslip␣someone's␣mindstereoisomerismsSt␣Martin's␣summers St.␣Martin's␣summerssubcommissionerssummer␣depressionswimming␣costumestaxonomic␣systemstissue␣committeestransmissometerstwist␣someone's␣armvictimless␣crimesWhitman's␣samplers

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