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There are 425 sixteen-letter words containing E, I, O, 2P and 2S

(page 3)

septorhinoplastyserpentinophytesshape␣up␣or␣ship␣outshipping␣forecastshopping␣trolleysshort-sea␣shippingSierpinski␣spongesilphiperfolenessimple␣microscopeSimpson␣Peninsulasloppy-mindednessSouth␣Pacific␣pesospace␣suppressionSpanish␣prisonersSpecial␣Olympiansspecies␣complexesspecies␣dysphoriaspectrinopathiessphincteroplastysphingolipidomessphingolipidosesspinous␣processesspiropiperidinessplit␣epimorphismsplit␣personalityspokespersonshipspokeswomanshipsspoonhead␣sculpinsporoplasmogenicsporopolleninoussportspersonshipspotted␣sandpiperspring␣in␣one's␣stepstaphyloplastiesstaphylorhaphiessteprelationshipstopping␣distancestopping␣servicesstreptocephalidsstylographic␣penssubinspectorshipsubtilopeptidasesulphinpyrazonessulphophosphitessupercompetitorssupercompressingsupercompressionsuperencryptionssuperexplosivelysuperexpressionssuperimpositions super-impositionssupermicroscopicsuperomnipresentsuperpanopticonssuperpersonalitysuperpolynomialssuperpopulationssuperpositioningsuperprestigioussuperprominencessuperpromiscuitysuperpromiscuoussuperproportionssupersuppressionsupplementationssupportabilitiessuppositiousnesssuppression␣ordersupraspliceosomesuspension␣pointssymplectic␣groupssymplesiomorphictelepolariscopestheophilosopherstheophilosophiestriosephosphates triose␣phosphatesunoppressivenessunpropitiousnessunsupportivenessupdate␣one's␣priorsuppies␣and␣downiesupsilon␣particlesvaccine␣passportsviolet␣phosphorusviscosupplementsvoter␣suppressionweapons␣inspectorWilson's␣phalaropexiphoid␣processesyuppie␣food␣stampszoopraxinoscopes

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