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There are 32 sixteen-letter words containing E, 2M, P and 3S

commissionershipcompression␣pumpscross␣peen␣hammersimmunosuppressedimmunosuppressesimmunosuppressorimmunosupressantimmunosupressionimmunosupressiveimpermissivenessimpossible␣dreamslymphatic␣systemsmass␣spectrometermass␣spectrometrymessiah␣complexesmetempsychosistsmetempsychosizesmicrocompressorsmisappraisementsneoimpressionism neo-impressionismpluries␣summonsespostmeasurementspromises,␣promisespseudosymmetriessemi-postal␣stampssimplemindedness simple-mindednessSimple␣Simon␣oversslip␣someone's␣mindsummer␣depressionWhitman's␣samplers

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