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There are 98 sixteen-letter words containing E, 2M, 2R and 2S

antisymmetrisersantisymmetrizersarylformamidasesasymmetric␣metersblue␣swimmer␣crabsCaesar's␣mushroomsChristmas␣marketscross␣peen␣hammersdesert␣rheumatismdisembarrassmentgammaherpesvirusgeometric␣isomershammerhead␣sharkshermaphroditismshierogrammatistshomoscleromorphshow␣embarrassmenthyperchromatismshyperconsumerismimmersion␣heatersimmunorepressiveimmunosuppressorimpostor␣syndromeintercommissurallateral␣meristemsmacrochromosomesmade␣matters␣worsemake␣matters␣worsemammarenavirusesMarshall␣syndromeMartinmas␣summersmass␣spectrometermass␣spectrometryMellin␣transformsmemorial␣servicesnière's␣syndromemeritorious␣mastsmessengers-at-armsmicrochromosomesmicrocompressionmicrocompressorsmicrohemispheresmicroinstrumentsmicroseismogramsmicroseismographmicroseismometermicroseismometrymicrospirometersmicrothermistersmicroviscometersmoral␣relativismsMorquio␣syndromesMorris␣water␣mazesmoules␣marinièresmurder␣simulatorsmushroom␣syndromeOmmaya␣reservoirson␣first-name␣termsorders␣of␣symmetryovermeasurementsparliamentarismspercussion␣hammerprometamorphosispromises,␣promisesprotochromosomesradial␣symmetriesreal␣number␣systemrefreshment␣roomsreverse␣commutersroeslerstammiidssame-sex␣marriagesSchrammel␣guitarsscreaming␣orgasmsseismocardiogramseismometrographsemibarbarianismshim-pua␣marriagesshort␣man␣syndromesilvery␣marmosetsSix's␣thermometersspherochromatismstage␣micrometersstereoisomerismsSt␣Martin's␣summers St.␣Martin's␣summersSumihiro's␣theoremsummer␣depressionsupercommutatorssuperdeterminismsuperprogrammerssupersymmetricalsupersymmetrizedthermocompressortrademark␣symbolstransmembraneoustransmissometerstranssarcolemmaltreeman␣syndromes

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