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There are 49 sixteen-letter words containing E, N, 2P, R and 2U

autoperpetuationbacteriopurpurinbutternut␣pumpkincolour␣supplementcountersupportedCyprus␣turpentineequal-opportunity equal␣opportunityfourspine␣sculpingroup␣punishmentshangs␣up␣one's␣spursimmunosuppresantimmunosuppresionimmunosuppresiveimmunosuppressedimmunosuppressesimmunosuppressormultipurposenessnecrosuppurativeneurosuppressionneurosuppressiveoverpopulousnesspeanut-butter␣cups peanut␣butter␣cupspermutation␣grouppharmacopuncturepick␣up␣one's␣crumbspicture-in-picturepleuroperitoneumpleuropneumoniaepneumoperitoneumporcupine␣pufferspresumptuousnesspseudoepipleuronpseudo-penannularpseudoprofundityrounds␣of␣applausesubperpendicularsupercomputationsuperpermutationsuperpopulationssupersuppressionunpremultiplyingunpresumptuouslyunpropitiousnessunprosperousnessunpurposefulnessunsupportivenessupper␣ten␣thousand

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