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There are 47 sixteen-letter words containing E, 2O, 2P and 2U

all-purpose␣floursautoperpetuationbuttons␣up␣one's␣lipcolour␣supplementcompound␣pendulumcountersupportedequal-opportunity equal␣opportunityimmunosuppresionimmunosuppressormorphosculpturedmorphosculpturesneurosuppressionoverpopulousnessoverpresumptuouspaulo-post-futurespedunculopontinepermutation␣grouppleuroperitoneumpleuropneumoniaepneumoperitoneumpolypseudonymouspseudocopulationpseudocopulatorypseudoepipleuronpseudoleukopeniapseudomorphouslypseudoplasmodiumpseudopopulationpseudoprofunditypseudopseudogoutpseudoviviparousPuestow␣procedurepulls␣one's␣socks␣uppulls␣up␣one's␣sockspurpureocobalticputs␣out␣to␣pasturerounds␣of␣applauseshape␣up␣or␣ship␣outsupercomputationsuperhaplogroupssupermacroporoussuperpopulationssuperpromiscuoussuppositiousnessunpropitiousnessunprosperousness

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