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There are 48 twenty-letter words containing 2E, 2M, 2S and U

adaptive␣immune␣systemarguments␣from␣silenceaugmented␣assignmentsbinary␣numeral␣systemscome␣to␣someone's␣rescuecommunicating␣vesselsCommunist␣News␣Networkcompensated␣summationcomplementary␣studiesconfessiones␣amantiumconstructive␣memoriescuts␣someone␣some␣slackEuropean␣Commissionerhammered␣dulcimeristsimmunoresponsivenessimmunosequestrationsintegumentary␣systemsJapanese␣mountain␣yamsjumping␣someone's␣bonesleast␣common␣multipleslittle␣summer␣of␣St␣Luke little␣summer␣of␣St.␣Lukemade␣someone's␣hair␣curlMagdeburg␣hemispheresmake␣someone's␣hair␣curlmake␣yourselves␣at␣homemelted␣someone's␣buttermesembryanthemaceousmesoeucrocodyliformsminimum␣spanning␣treesmultimillionairessesmultiple␣transformersnonimmunosuppressiveoverimmunosuppressedpremenstrual␣syndrome pre-menstrual␣syndromesame,␣same,␣but␣differentseasonal␣unemploymentshome␣mishtake␣shurelyshurely␣shome␣mishtakeSister␣Souljah␣momentssodium␣metabisulphitesomatic␣nervous␣systemsummer␣penile␣syndromesupersymmetrizationstime␣and␣motion␣studiestransuranium␣elementsureterosigmoidostomy

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