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There are 52 twenty-one-letter words containing 2E, M, P, R and 2U

absolute␣primogenitureargumentum␣ad␣passionesauriculotemporal␣nerveAustro-Hungarian␣Empireautonomous␣prefecturesbuild␣a␣better␣mousetrapcapnopneumoperitoneumcheckups␣from␣the␣neck␣upcomputationally␣securecomputer␣architecturesconclusive␣presumptionelectric␣multiple␣unitsGuadalupe␣storm␣petrelshaemopneumoperitoneumimmunotherapeuticallyimperfect␣subjunctivesjump␣before␣one␣is␣pushedliquefied␣petroleum␣gasmetal␣cluster␣compoundsmetallosupramolecularmononeuritis␣multiplexmultiplicative␣numbersmultiplicative␣numeralnuclear␣magnetic␣pulsesoverimmunosuppressionpercussion␣instrumentspleuropneumonectomiespneumohemopericardiumpremature␣ejaculationspreoperculomandibularpressure␣volume␣diagrampseudopharmaceuticalspseudosclerodermatouspunctuated␣equilibriumpurely␣imaginary␣numberputs␣a␣bug␣in␣someone's␣earquantum␣teleportationsrecherche␣du␣temps␣perduRomeo␣and␣Juliet␣couplesrubber␣baby␣buggy␣bumpersaturation␣temperaturespotted␣cucumber␣beetlesupercompound␣interest super-compound␣interestsuperior␣oblique␣musclesupernumerary␣rainbowssuperparticular␣numbersurplus␣to␣requirementsunemployment␣insurancewestern␣spruce␣budwormswhat␣is␣your␣phone␣numberyou␣must␣be␣fun␣at␣parties

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See this list for:

  • Scrabble in English: no word
  • French Wiktionary: 167 words
  • Spanish Wiktionary: 1 word
  • Italian Wiktionary: no word
  • German Wiktionary: 59 words
  • Portuguese Wiktionary: 3 words
  • Dutch Wiktionary: 35 words

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