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There are 40 twenty-one-letter words containing 2E, O, 3P and S

adenylpyrophosphataseamplitude␣spectroscopyapologetic␣apostrophesCalifornia␣pepper␣treescompare␣apples␣to␣applescyclohexadepsipeptidecyclooctadepsipeptideEuropean␣pond␣terrapinsfarnesylpyrophosphatefibroepithelial␣polypshyperlipoproteinemiashypoelliptic␣operatorsinfraprezygapophysealinterprezygapophysealintraprezygapophyseallipodepsinonapeptideslipotetradecapeptidesnucleophosphoproteinspeacock␣jumping␣spiderspeephole␣optimizationspentaphosphaferrocenepeptidopolysaccharideperpendicular␣pronounspersonal␣property␣taxespharyngoesophagoscopePhilippine␣cuckoo-dovesphosphopeptidomimeticPolish␣People's␣Republicpolluter␣pays␣principlepop␣a␣cap␣in␣someone's␣arsepopping␣someone's␣cherrypops␣a␣cap␣in␣someone's␣asspostalveolo-prepalatalreciprocity␣principlessingle-page␣applicationspeculative␣philosophyspinoprezygapophysealsupraprezygapophysealtypewriter␣apostrophesupper␣respiratory␣tract

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See this list for:

  • Scrabble in English: no word
  • French Wiktionary: 43 words
  • Spanish Wiktionary: no word
  • Italian Wiktionary: no word
  • German Wiktionary: 7 words
  • Portuguese Wiktionary: no word
  • Dutch Wiktionary: 12 words

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