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There are 86 twenty-one-letter words containing E, 2I, 2M and 2S

abdominohysterotomiesadaptive␣immune␣systemsalgorithmic␣randomnessappointments␣in␣Samarraarguments␣from␣illusionasymmetrical␣spinnakerautonomous␣communitiesbackwards␣time␣machinescerebromicroembolismsChamisha␣Chumshei␣TorahChinese␣Communist␣Partycombined␣braking␣systemcomiconomenclaturistscommand␣responsibilitycommissions␣de␣bene␣essecommitting␣magistratescompartmentalisationscrimes␣against␣humanitydegrammaticalisationsdiscriminative␣stimulidysgammaglobulinemiasemphysematous␣cystitisestablishmentarianismEuropean␣CommissionersformiminotransferasesFrobenius␣endomorphismgammapapillomavirusesgreatest␣common␣divisorhistorical␣materialismhuman␣papillomaviruseshyperemesis␣gravidarumhyperhomocysteinemiasimmunoelectrophoresisimmunophotosensitizerimmunoreconstitutionsImperial␣stormtroopers Imperial␣Stormtroopersinquisition␣post␣morteminstitutional␣memoriesion-selective␣membranesIslamic␣fundamentalismlibertarian␣communistsLord␣High␣CommissionersMalaysian␣flying␣lemursMarxism-Leninism-Maoismmathematical␣semanticsmeadow␣grass␣dermatitismembrane␣distillationsmetaconstitutionalismmicrothromboembolismsMississippi␣windchimes Mississippi␣wind␣chimesMitchell's␣hopping␣mousemonofixation␣syndromesmore␣life␣in␣a␣tramp's␣vestmultidimensionalitiesmultiinstrumentalists multi-instrumentalistsnew␣religious␣movementsnight-blooming␣jasminesnominative␣type␣systemsnon-commissioned␣memberoverimmunosuppressionphysicomathematicianspneumocystis␣pneumoniapollution␣permit␣systemproctosigmoidectomiespseudohermaphroditismregional␣metamorphismsretrospective␣memoriesRevisionist␣Maximalismrhinitis␣medicamentosarustle␣someone's␣jimmiessarcoplasmic␣reticulumSchneiderian␣membranesscientific␣materialismsemiconductor␣memoriessemigroup␣homomorphismsemipalmated␣sandpiperSimmons-Smith␣reactionssimple␣harmonic␣motionssliding␣filament␣modelssmoked␣salmon␣socialistsonochemiluminescenceswap␣horses␣in␣midstreamtook␣something␣as␣it␣came

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