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There are 44 twenty-one-letter words containing E, I, 2M, P, S and Y

absorption␣dynamometeradaptive␣immune␣systemsasymmetrical␣spinnakeratomic␣force␣microscopyChinese␣Communist␣Partyclassical␣unemploymentcommand␣responsibilitydimethoxyamphetaminesemphysematous␣cystitisexploratory␣committeeshighly␣composite␣numberhistomorphometricallyhomogeneous␣polynomialhomogenous␣polynomialshyperemeses␣gravidarumhyperemesis␣gravidarumhyperhomocysteinaemiahyperhomocysteinemiasimprovisational␣comedylittle␣emperor␣syndromelymphoblastic␣leukemiamagnetoplasmadynamicsMalecite-PassamaquoddyMaliseet-Passamaquoddy Maliseet–Passamaquoddymedial␣pterygoid␣musclemethylphenethylaminesnominative␣type␣systemspharmacophylogenomicsphotomechanochemistryphysicomathematicallyphysicomathematicianspillars␣of␣the␣communityPlummer-Vinson␣syndromepneumocystis␣pneumoniapollution␣permit␣systemprimary␣reinforcementspsychoneuroimmunologysecond␣impact␣syndromessilane-modified␣polymersphygmomanometricallytrimethaphan␣camsylateunemployment␣insuranceyellow-rumped␣mannikins

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See this list for:

  • Scrabble in English: no word
  • French Wiktionary: 24 words
  • Spanish Wiktionary: no word
  • Italian Wiktionary: no word
  • German Wiktionary: 2 words
  • Portuguese Wiktionary: no word
  • Dutch Wiktionary: 6 words

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