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There are 40 twenty-one-letter words containing E, 2M, P, 2S and U

adaptive␣immune␣systemsargumentum␣ad␣passionesChinese␣Communist␣Partyclassical␣unemploymentcome␣up␣smelling␣of␣rosescompensated␣summationscompensation␣pendulumscompliments␣of␣the␣houseemphysematous␣cystitisEuropean␣CommissionersFrobenius␣endomorphismgammapapillomaviruseshomogenous␣polynomialshuman␣papillomaviruseshyperemeses␣gravidarumhyperemesis␣gravidarumimmunoelectrophoresesimmunoelectrophoresisimmunophotosensitizerinquisition␣post␣mortemlowest␣common␣multiplesMalecite-PassamaquoddyMaliseet-Passamaquoddy Maliseet–Passamaquoddymetal␣cluster␣compoundsMitchell's␣hopping␣mouseoverimmunosuppressionPlummer-Vinson␣syndromepneumocystis␣pneumoniapollution␣permit␣systempotassium␣permanganatepressure␣makes␣diamondspressure␣volume␣diagrampseudohermaphroditismrubber␣stamp␣committeesSan␣Pedro␣Amuzgos␣Amuzgosarcoplasmic␣reticulumsemigroup␣homomorphismThompson␣submachine␣gunupsetting␣thermometers

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See this list for:

  • Scrabble in English: no word
  • French Wiktionary: 80 words
  • Spanish Wiktionary: no word
  • Italian Wiktionary: no word
  • German Wiktionary: 50 words
  • Portuguese Wiktionary: 2 words
  • Dutch Wiktionary: 29 words

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