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There are 126 ten-letter words containing I, O, P and 2U

aquiparousaspiculousauspiciousauspitiousautopodiumbiosulphurbuilds␣uponcajuput␣oilchoupiquescompluviumcoughing␣upcounting␣upcucumopinecultigroupcupidinouscupuliformdieuropiumdoubling␣upepicureousepicuriouseupatoriumeuphoniouseuphoniumseuphorbiumgaluptiousgoluptioushot␣pursuitimmunopureimportuousjumping␣outjunior␣jumpLauniupokoliquored␣uplumpatiousmuciparousmultigroupmultipoundmusic␣groupnonpursuitnuliparousouroupariaoutjumpingoutpouringoutpuffingoutpullingoutpushingoutputtingpaludinouspancurious pan-curiouspauciloquypediculouspericulousperitumourperjuriousphoulouriephulouriespious␣fraudplumptiousplutoniumsponticulusPope␣Juliuspreludiousprociduousproficuousprofluviumpropudiouspubic␣lousepubic␣moundpubigerouspugnaciouspulling␣outpultrusionpumping␣outpunking␣outpupigerouspupiparouspupivorouspurdoniumspushing␣outpustulosisput␣it␣aboutputting␣outpyrocumuliquasigroupquid␣pro␣quoquo␣pro␣quidroughing␣uprounding␣uprupicoloussodium␣pumpspirituousspuriouslysuboptimumsubspinoussuction␣cupsulphoniumsuperbioussuperiourssuperpioussuppositumsuspicioussuspirioustorquing␣uptouching␣uptubuliporeultrapiousuncaptiousuncouplinguneuphonicungroupingunoccupiedunperilousunpreciousunspaciousunspeciousunspuriousunsuperiorupmountainuproariousupspoutingUruk␣periodusucapionsusucaptionusurpationvituperous

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