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There are 95 sixteen-letter words containing 2I, 2U and Y

absolute␣humidityabsolute␣immunityalkenylaluminiumaluminium␣hydrideauthority␣figuresautoreducibilityautoubiquitylateauxiliary␣cruiserbutylimidazoliumcan␣I␣buy␣you␣a␣drinkcircumlocutorilyconsuetudinarilycryosubstitutioncultural␣identitydeubiquitylatingdeubiquitylationdiethylaluminiumdihydrofusarubinequicontinuouslyFebruary␣Uprisingfunicular␣railwayhyperalbuminuriaimmunosurgicallyimmunoturbimetryindustry␣discountinterculturalityintracuticularlyisostructuralityKangiryuarmiutunmakuuchi␣dohyo-irimonoubiquitylatemulticellularitymulticulturalitymultigranularitymultisingularitymultivesicularlymurders␣by␣suicideoversuspiciouslyPacific␣Gulf␣Yupikpainfully␣obviousperibunyavirusespluricellularitypolyautoimmunitypolyubiquitinatepolyubiquitylatepseudouridimycinpyrosulfuric␣acidquantity␣discountquantum␣mysticismSaint␣Louis␣Countysemicontinuouslysexuality␣studiessubstitutabilitysubstitutionallysulfocysteinuriasulfopyruvic␣acidsuperdiffusivelysuperdiffusivitysupermasculinitysuperpromiscuitysupposititiouslysupraumbilicallytriethylaluminumturbidity␣currentubiquitinylatingubiquitinylationultramasculinityunaccountabilityunaltruisticallyunconquerabilityundisputatiouslyunextinguishablyuninfluentialityunistructuralityunitary␣authorityunjustifiabilityunparsimoniouslyunperturbabilityunpremultiplyingunpublishabilityunpurchasabilityunrelinquishablyunscrutinizinglyunshuffleabilityunsubstantialityunsupportabilityunsusceptibilityunsustainabilityutility␣computingutility␣functionsutility␣furniturevirtual␣communitywukipolyomavirusyou␣can't␣fix␣stupidyuanyang␣hudie␣pai

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See this list for:

  • Scrabble in English: no word
  • French Wiktionary: 56 words
  • Spanish Wiktionary: no word
  • Italian Wiktionary: no word
  • German Wiktionary: 2 words
  • Portuguese Wiktionary: no word
  • Dutch Wiktionary: 2 words

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