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There are 565 eighteen-letter words containing 2I, P, S and Y

(page 3)

oscillographicallyosteocompatibilityotomicroscopicallyoveroptimisticallyoverpsychologizingoversimplisticallyoversusceptibilitypachyrhizodontoidspalaeobiochemistrypalaeobiodiversitypaleoichthyologistpaleophysiologicalpanhypopituitarismparalinguisticallyparalytic␣dementiasparascientificallyParry␣Sound␣Districtparsimony␣principlepathophysiologicalpathophysiologistspatristic␣anthologypayload␣specialistsPennsylvania␣riflespepsinhydrochloricpeptidoglycolipidspeptidylnucleosideperitoneal␣dialysispharyngealizationspharyngointestinalpharyngolaryngitispharyngotonsilitisphenylboronic␣acidsphilosophers␣by␣firephloroglucinolysisphosphatidylserinephosphoglycolipidsphosphoselectivityphosphosensitivityphosphospecificityphotophysiologicalphotoreversibilityphotoswitchabilityphycoerythrobilinsphyletic␣gradualismphylobetadiversityphylostratigraphicphysical␣distancingphysical␣quantitiesphysical␣therapistsphysician␣assistantphysician␣extendersphysicochemicalismphysicomathematicsphysicotheologicalphysiobiochemistryphysiogeographicalphysiopathogenesisphysiopathologicalphysiopathologistsphytophysiognomiesphytophysiologicalphytostabilisationphytostabilizationPiccadilly␣butcherspiezopsychrophilicpiperonylonitrilespiriformis␣syndromePittsylvania␣Countyplay␣the␣dickens␣withpoikiloblasticallypolicy␣interest␣ratepolyacrylonitrilespolybenzimidazolespolydispersibilitypolydispersivitiespolyesterificationpolyethyleneiminespolyfunctionalisedpolymerizabilitiespolymerogenicitiespolymolecularitiesPolynesian␣Trianglepolyphosphoric␣acidpolyvictimizationspolyvinylchlorides polyvinyl␣chloridespolyvinylsiloxanespopulation␣pyramidspositional␣asphyxiapositive␣neutralitypostdepositionallypostdiagnosticallypostlinguisticallypostpericardiotomypostpolymerizationpotassium␣hydroxidepotentiostaticallyprecompositionallyprecrystallizationpredispositionallypreliminary␣rulingsPresidency␣divisionpresuppositionallypresynchronizationprimary␣legislationprimary␣transcriptsprobability␣densityprobability␣measurepropagandisticallypropionylpromasineproposition␣playerspropriosensitivityprosecution␣historyprosperity␣doctrineprotodesilylationsprotomicrocotylidsproximoposteriorlypseudobiologicallypseudoheritabilitypseudouridylationspseudoxyrhophiinespsychoacousticianspsychobiographicalpsychobiologicallypsychocivilizationpsychogeriatricianpsychohistoricallypsycholinguisticalpsychological␣slipspsychologisticallypsychomanipulationpsychomanipulativepsychophilosophiespsychophysiologistpsychosemioticallypsychosociologicalpsychosociologistspsychosomatizationpsychostimulationspsychrosensitivitypulmonary␣docimasiapyridylsulfoximinepyrimidodiazepinespyrophosphoric␣acidpyropoikilocytosisqualifying␣positionrectosigmoidoscopyrespiratory␣pigmentreticulocytopeniassalpingoscopicallysalpingovariectomy

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See this list for:

  • Scrabble in English: no word
  • French Wiktionary: 705 words
  • Spanish Wiktionary: 9 words
  • Italian Wiktionary: no word
  • German Wiktionary: 61 words
  • Portuguese Wiktionary: no word
  • Dutch Wiktionary: 19 words

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