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There are 26 words containing I, R, U and 2X

Bordeaux␣mixturecefuroxime␣axetilcoexecutrixcoexecutrixescrux␣simplexdeoxydoxorubicindexproxibuteneexcitoneurotoxicityexecutrixexecutrixesexecutrixshipexecutrixshipsexodeoxyribonucleaseexodeoxyribonucleasesextracellular␣matrixextratextualityhydroxydeoxyguanosineneuroexcitotoxicneuroexcitotoxicityout-of-box␣experienceout-of-box␣experiencessexual␣anorexiasexual␣anorexicsexual␣anorexicssexually␣anorexicsurgerymaxxing

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See this list for:

  • Scrabble in English: 4 words
  • French Wiktionary: 155 words
  • Spanish Wiktionary: no word
  • Italian Wiktionary: no word
  • German Wiktionary: no word
  • Portuguese Wiktionary: 1 word
  • Dutch Wiktionary: no word

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