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There are 280 twenty-one-letter words containing I, L, M, R and 2S

abdominoscrotal␣muscleabominable␣snow␣monsteradmiral␣of␣the␣Swiss␣Navyalgorithmic␣randomnessalphapapillomavirusesAmerican␣cliff␣swallowsaminoacyltransferasesamplitude␣spectroscopyanterior␣scalene␣muscleantienvironmentalists anti-environmentalistsantitranscendentalismarguments␣from␣illusionarm's␣length␣transactionasteroseismologicallyastronomical␣transientasymmetrical␣spinnakerAustralasian␣slimwingsbarking␣dogs␣seldom␣biteBehrens-Fisher␣problemsbicameral␣legislaturesbinomial␣distributionsblack␣over␣Bill's␣mother'sblew␣someone's␣brains␣outblow␣someone's␣brains␣outbrass␣instrumentalistsbreaking␣someone's␣ballsbuckminsterfullerenesburning␣nuclear␣plasmasbus␣replacement␣servicecamphorsulphonic␣acidscardiovascular␣systemsCarolingian␣minusculescentral␣simple␣algebrascerebromicroembolismsChinese␣postman␣problemChristian␣UniversalismChristmas␣caterpillarsClaisen␣rearrangementsclass-based␣programmingcollectivist␣anarchismcome␣up␣smelling␣of␣rosescomfortable␣in␣one's␣skincomiconomenclaturistscommand␣responsibilitycommon␣squirrel␣monkeyscompartmentalisationscompositional␣grammarsconclusive␣presumptionconstructive␣dismissalcosmological␣argumentsCotswold␣morris␣dancingcounterestablishmentscriminal␣psychologistscurse␣of␣dimensionalitycyclomaltodextrinasesdeacetylmarsformosidedegrammaticalisationsdemonstrative␣legaciesdermatovenereologistsdihydrosphingomyelinsdiscriminative␣stimulidisestablishmentariandisseminated␣sclerosiseastern␣imperial␣eagleselastomucoproteinaseselectrochemical␣serieselectromagnetic␣pulseselectromethanogenesisenvironmental␣scienceserythroleukemogenesisestablishmentarianismesthesioneuroblastomaEuropean␣swamp␣thistlesFallen␣Jerusalem␣Islandfiddles␣while␣Rome␣burnsfirm␣hands␣at␣the␣tillersfirm␣hands␣on␣the␣tillersfirst␣cosmic␣velocitiesforum␣selection␣clausesFrankenstein␣complexesgalactosylceramidasesgammapapillomavirusesganglioneuroblastomasgluttons␣for␣punishmentgulosarmentoglucosidehistorical␣materialismhomeotransplantationshuman␣papillomaviruseshydraulic␣Keynesianismhypercholesterolemiashypercholesterolemicsill␣doers␣are␣ill␣deemersimmunoelectrophoresesimmunoelectrophoresisimmunopharmacologistsImperial␣stormtroopers Imperial␣Stormtroopersinclusion␣polymorphismincomprehensibilitiesinformationalisationsinstitutional␣memoriesintergovernmentalistsion-selective␣membranesisostoichiometricallyJudeo-Christian-IslamicKemp's␣ridley␣sea␣turtleskick␣bollocks␣scramblesKöhlmeier-Degos␣diseaseleaves␣much␣to␣be␣desiredLevy-Hollister␣syndromelibertarian␣communistslike␣molasses␣in␣Januarylinear␣transformationslittle␣bluestem␣grasseslittle␣summers␣of␣St␣Luke little␣summers␣of␣St.␣Luke

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