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There are 132 sixteen-letter words containing 2I, O, 2S and 2U

aluminium␣showersantituberculosisarboriculturistsaudiovisualitiesback␣substitutionbituminous␣shalesburning␣questionsbursa␣of␣Fabriciuscircumcursationsconcupiscentiousconsuetudinariescryosubstitutiondemutualisationsdesulfuricationsdesulfurizationsdesulphurisationdisingenuousnessdisputatiousnessequiparsimoniousfistulous␣withersFitting␣subgroupsfourspine␣sculpinfree␣substitutionGaussian␣functionhousefurnishingsimmunodiffusionsimmunosignaturesimmunostimulantsimmunosubversionimmunosubversiveimmunosuppresionimmunosuppresiveimmunosupressionimmunosupressiveimpulse␣functionsinauspiciousnessindustry␣discountinobsequiousnessinsalubriousnessinsulin␣analoguesintussusceptionsisoquinuclidinesisostructuralityjuniper␣titmousesleucosulfakininsLissajous␣figuresludomusicologistluminous␣energiesmetasubstitutionMissouri␣currantsmonosubstitutionmucilaginousnessmultifariousnessneurolinguisticsnitrosubstitutednonsubstitutionsnonsuperstitiousnouvelle␣cuisinesokuritsuriotoshiostreiculturistsoutsider␣musicianoversubstitutionoversuspiciouslyparasubstitutionpotassium␣sulfiteprevious␣questionprostitute's␣pupilpseudoaltruisticpseudocellulitispseudodiffusionspseudoinclusionspseudoinfectiouspseudolinguisticpseudoviviparouspublishing␣housespub␣quiz␣questionspunctualisationsquerimoniousnessreligious␣studiesremutualisationsridiculousnessesSaint␣Louis␣CountySaint-Louis-du-Ha!␣Ha!sanguineobilioussaussuritizationsemicontinuouslysodium␣bisulphatesodium␣bisulphitesoup-and-fish␣suitsstructurationiststructurizationssubcartilaginoussubdistributionssubfunctionalisesubinfeudatoriessubstitutionallysubstitution␣codesub-superstitionssuburbanisationssuburbanizationssulfocysteinuriasulfosuccinimidesulfur␣impressionsuperciliousnesssupercommunitiessuperindustrioussuperinjunctions super-injunctions super␣injunctionssuperinstitutionsuperprestigioussuperpromiscuitysuperstimulationsuppositiousnesssupposititiouslysurviving␣spousestrisubstitutionstuberculisationsturn␣in␣successionturquoiseberriesultraprestigiousunauspiciousnessundisputatiouslyunfastidiousnessunfelicitousnessuninfectiousnessunparsimoniouslyunpropitiousnessunsolicitousnessunsubstantiationunsuspiciousnessviruliferousness

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