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There are 44 twenty-letter words containing I, O, 3S and 2U

absolute␣instructionsabsolute␣superlativesalarums␣and␣excursionsAustralodelphis␣mirusconditions␣subsequentconscious␣uncouplingsconspicuous␣consumerscounterdistinguisheseuglobulin␣lysis␣timesEurasian␣stone-curlewsGaussian␣distributionheterokurtosis-robustimmunosequestrationsintraocular␣pressuresnonimmunosuppressantnonimmunosuppressiveobscurum␣per␣obscuriusoverimmunosuppressedpercussion␣instrumentposthumous␣executionspseudopseudoseizuresput␣someone's␣lights␣output␣the␣shits␣up␣someonereligious␣naturalistsresidual␣sum␣of␣squaresrusset␣ground␣squirrelsesquiple␣first␣cousinshining␣tubeshouldersSouthern␣United␣StatesSouth␣Gloucestershiresouth-southeasterliessouth-southwesterliesstands␣up␣and␣is␣countedstatutory␣instrumentsstructural␣isomerismsstupid␣is␣as␣stupid␣doessubcommissural␣organssubsynchronous␣orbitssun-synchronous␣orbitssuperfluous␣intervalssuperior␣tarsal␣muscleswings␣and␣roundaboutsunderpressurizationsuniverses␣of␣discourse

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