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There are 58 twenty-one-letter words containing I, O, P, 2S and 2U

argumentum␣ad␣passionesAsk␣a␣Stupid␣Question␣Dayauriculares␣superioresbutterflies␣upon␣wheelscasualty␣of␣superioritycompensation␣pendulumsconclusive␣presumptioncounterproductivenessdesulphoglucosinolateequipotential␣surfacesgluttons␣for␣punishmenthigh-fructose␣corn␣syrup high␣fructose␣corn␣syruphuman␣papillomaviruseshydrodesulphurisationjump␣before␣one␣is␣pushedmalicious␣prosecutionsnitrosylsulphuric␣acidnoun␣substantive␣properout-of-school␣suspensionoverimmunosuppressionpast␣perfect␣continuouspercussion␣instrumentspneumocystis␣pneumoniapressure␣volume␣diagrampropositional␣calculuspseudoepitheliomatouspseudointellectualismpseudomultiplicationspseudopharmaceuticalspseudorevolutionariespulling␣out␣all␣the␣stopspulmonary␣tuberculosispunctus␣interrogativuspushed␣the␣right␣buttonspushes␣the␣right␣buttonsputs␣a␣bug␣in␣someone's␣earquantum␣processing␣unitrequests␣for␣productionrufous-capped␣antshrikesarcoplasmic␣reticulumsee␣you␣in␣the␣funny␣pagesspinal␣muscular␣atrophyspontaneous␣combustionsquad␣automatic␣weaponssupercompound␣interest super-compound␣interestsupergranulation␣cellssuperior␣oblique␣musclesuperior␣petrosal␣sinussuperior␣sagittal␣sinussupernatural␣selectionsupernumerary␣rainbowsSuperstition␣Mountainssurplus␣to␣requirementsThompson␣submachine␣gununiversal␣product␣codesyou␣must␣be␣fun␣at␣parties

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See this list for:

  • Scrabble in English: no word
  • French Wiktionary: 177 words
  • Spanish Wiktionary: 2 words
  • Italian Wiktionary: no word
  • German Wiktionary: 34 words
  • Portuguese Wiktionary: no word
  • Dutch Wiktionary: 21 words

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