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There are 53 twenty-one-letter words containing I, O, P, 2T and 2U

absolute␣primogenitureAsk␣a␣Stupid␣Question␣Daybuild␣a␣better␣mousetrapbutterflies␣upon␣a␣wheelbutterflies␣upon␣wheelscasualty␣of␣superioritycomputationally␣securecomputer␣architecturescounterproductivenessCouva-Tabaquite-Talparocultural␣appropriationcultural␣appropriatorsculturally␣appropriatecultural␣phylogeneticscultural␣practitionersduplications␣of␣the␣cubeequipotential␣surfacesEuropean␣penduline␣titsfall␣off␣the␣turnip␣truckfell␣off␣the␣turnip␣truckgluttons␣for␣punishmentgreat␣grand␣multiparousimmunotherapeuticallymononeuritis␣multiplexnoun␣substantive␣properout-paramouring␣the␣Turkpast␣perfect␣continuouspercussion␣instrumentspremature␣ejaculationspseudoepitheliomatouspseudointellectualismpseudomultiplicationspulling␣out␣all␣the␣stopspulmonary␣function␣testpunctus␣interrogativuspushed␣the␣right␣buttonspushes␣the␣right␣buttonsputs␣through␣the␣wringerquantum␣processing␣unitquantum␣teleportationsrequests␣for␣productionretrotrapezoid␣nucleussaturation␣temperaturespontaneous␣combustionsquad␣automatic␣weaponsstructured␣programmingsupercompound␣interest super-compound␣interestsuperior␣sagittal␣sinussupernatural␣selectionSuperstition␣Mountainssurplus␣to␣requirementsyou␣must␣be␣fun␣at␣parties

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See this list for:

  • Scrabble in English: no word
  • French Wiktionary: 105 words
  • Spanish Wiktionary: 3 words
  • Italian Wiktionary: 1 word
  • German Wiktionary: 45 words
  • Portuguese Wiktionary: no word
  • Dutch Wiktionary: 19 words

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