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There are 65 sixteen-letter words containing N, O, 2P and 2U

autoperpetuationavoirdupois␣poundbacteriopurpurinbuttons␣up␣one's␣lipchew␣up␣and␣spit␣outchuck␣up␣the␣spongecolour␣supplementcompound␣pendulumcorpus␣spongiosumcountersupportedequal-opportunity equal␣opportunityfourspine␣sculpingroup␣punishmentshangs␣up␣one's␣spursimmunosuppresantimmunosuppresionimmunosuppresiveimmunosuppressedimmunosuppressesimmunosuppressorinput-output␣tablemultipurposenessnecrosuppurativeneurosuppressionneurosuppressiveoverpopulousnesspedunculopontinepermutation␣grouppharmacopuncturepick␣up␣one's␣crumbspleuroperitoneumpleuropneumoniaeplum␣pudding␣modelpneumoperitoneumpolypseudonymousporcupine␣pufferspresumptuousnesspseudocopulationpseudoepipleuronpseudoleukopeniapseudo-penannularpseudopopulationpseudoprofunditypulls␣one's␣socks␣uppulls␣up␣one's␣sockspunctuation␣spacepunitive␣populismrounds␣of␣applausesubhaplogroupingsubsubpopulationsupercomputationsuperpermutationsuperpopulationssupersuppressionsuppositiousnesssuprapopulationsturn␣into␣a␣pumpkinunpresumptuouslyunpropitiousnessunprosperousnessunpurposefulnessunsupportabilityunsupportivenessupper␣ten␣thousand

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