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There are 441 twelve-letter words containing O, P, T and X

adelphotaxonamfepentorexantiexposureantipoxviralantipoxvirusantismallpoxapex␣predatorapproximantsapproximatedapproximatesapproximatorarcheopteryxasphyxiationasphyxiatorsasphyxiatoryautoasphyxiaautoexposureautoprefixerauxetophonesauxotrophiesauxotrophismaxonopathiesaxonotrophicaxoplasmaticblaxploitersbox␣operatorsbutylperoxylcanthopexiescentropyxidscephalotoxinchartophylaxclopenthixolcomplexationcomplexitiescomplexitonscompurgatrixcoredemptrixcorporate␣taxcostoxiphoidcourt␣poor␣boxCoxeter␣graphCoxeter␣groupcoxopleuritecryptoexoticcrypto-sexismcryptosexist crypto-sexistcytophylaxisdaxophonistsdecomplexantdeoxyheptosedeoxypentosedepixelatorsdexpanthenoldextofisopamepigenotoxicepoxidationsepoxygenatedepoxyketoneseuxerophyteseuxerophyticexaptationalexasperationexasperatorsexceptionalsexceptionersexceptionistexculpationsexecutorshipExeter␣pointsexit␣policiesexit␣programsexoanthropicexoccipitalsexoenthalpicexooccipitalexoparasitesexopathogensexopectinaseexopeptidaseexophenotypeexophthalmiaexophthalmicexophthalmosexophthalmusexophyticityexoplanetaryexoproteasesexoproteomesexoproteomicexopterygoteexosomopathyexotic␣sphereexpansionistexpatiationsexpatriationexpectationsexpectorantsexpectoratedexpectoratesexpectoratorexpeditationexpeditionedexpeditionerexpertocracyexpertocratsexpiatoriousexpirationalexpiscationsexplainationexplanationsexplantationexplicationsexploitablesexploitationexploitativeexploitatoryexploiteringexploitivelyexplorationsexploratoriaexploratressexplorementsexplosimeterexpoliationsexponentialsexponentiateexpontaneousexportationsexposimetersexpositionalexpositorilyexpostulatedexpostulatesexpostulatorexpotentiateexprobratingexprobrationexprobrativeexprobratoryexpropriatedexpropriatesexpropriatorexpugnationsexpulsationsexpulsionistexpurgationsexspoliationex-stepmotherextemporallyextemporaneaextemporaniaextemporisedextemporiserextemporisesextemporizedextemporizerextemporizesextensographexteroceptorextirpationsextispiciousextrapolatedextrapolatesextrapolatorextrapontineextrapopularextratropicsextreme␣pointextreme␣sportextremophileextremophyteextroceptiveextropianismextrospectedexuviotrophsfauxtographsfauxtographyflupenthixolgastropexiesgoogolplexthguilt␣complexhapaxanthousheat␣apoplexyhepatotoxinshepatoxicityheptahydroxyheteroduplexhexapetaloushyperoxidanthypotoxicityhypoxanthineideopraxistsimperatoxinsincomplexityintercomplexintracomplexjuxtaposablejuxtaposingsjuxtapositedjuxtapyloriclexitropsinslipotoxicitylipoxidationlipoxidativelipoxygenatelymphotoxinsmatrix␣groupsmaxicomputermetal␣complexmicroexplantmisexploitedmorphosyntax morpho-syntaxmulticomplexmultiplexorsnephrotoxinsNitro␣Expressnitrophenoxynonexemptionnonexploitednonexportingnonhypertextnonmultiplexnonproximatenontaxpayersnontaxpaying

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