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There are 44 five-letter words containing O, P, S and U

BOPUScopuscoupsCuposdoupsFOUPsHoupsloupsLuposmopusOPSEUouphspiousPOCUSPolusporus PorusPOTUSpoudspoufspouispourspoutspro-USpuoysPupospurosputosquopsroupsShoupsop␣upsoupssoupyspoutsquopstoupToupstuposupdosUpsonupsotU.S.␣G.P.O.USPTO

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