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There are 252 ten-letter words containing O, P, S and 2U

aquiparousasperulousaspiculousauspiciousauspitiousbiosulphurbuilds␣uponchoupiquesconjures␣upcorpusculecough␣syrupcounts␣coupcupidinousdoshpuluurdrupaceousduopluralsepicureousepicuriousescrupuloseuphoniouseuphoniumsEurogroupseurypylouseusauropodfocus-group focus␣groupfunduscopefunduscopygaluptiousgoluptioushemosputumhocuspocus hocus-pocus hocus␣pocushot␣pursuithouseproud house-proud house␣proudimportuousjokulhaupsloup-garouslow-sulphurlumpatiousmagnum␣opusmouth-pussymuciparousmusic␣groupneurolupusnonpursuitnonsulphurnonsurplusnuliparousopus␣magnumoutcouplesoutpourersoutpunchesoutpushingoutput␣armsoutputtersoutspoutedoutspurtedoutsurpassoverpursuepaludinouspalustrouspancurious pan-curiouspatulouslypediculouspenumbrouspericulousperjuriousperpetuousphulouriespious␣fraudpleasurouspleurosaurplumaceousplumptiousplunderousplutoniumspolybunousponticulusPope␣Juliuspopulouslypopup␣menus pop-up␣menusPortuguesepostbuyoutpostcaucusposthumous post-humouspostulatumpouchesfulpouncehugsPoundesquepreludiousprociduousprocureursproficuousproloculuspronucleuspropudiousprunaceouspseudobubopseudobulbpseudobulkpseudocusppseudodualpseudogoutpseudonullpseudopupapseudoureapuberulouspubic␣lousepubigerouspuerperousPuget␣Soundpugnaciouspull-quotes pull␣quotespull-up␣boyspulpaceouspultaceouspultrusionpumphouses pump␣housespunches␣outpunch␣housepuntaboutspupigerouspupiparouspupivorouspurdoniumspuromucouspurposefulpurseproud purse-proudPurshousespurveyourspush␣aroundpushbutton push-button push␣buttonpushed␣up␣onpushes␣up␣onpushing␣outpustulosisput␣spurs␣toput␣up␣a␣showpuzzles␣outquasigrouprough␣pumpsroughspunsrumpus␣roomrupicolousscrounge␣upscrupuloussculptourssexuparousshut␣up␣shopsodium␣pumpsoup␣de␣joursoup␣du␣joursoup-to-nutssourpusses sour␣pussesspherulousspirituousspuriouslysputter␣outstrophulusStroustrupstubborn␣upstudy␣groupstupendoussubgroupedsuboctuplesuboptimumsubproductsubpurposesubspinoussuction␣cupsulfur␣soapsulphoniumsulphur␣oresulphuroussummer␣soupsummoned␣upsun␣parloursuperbioussuperboundsupercloudsupergroupsuperhousesuperiourssuperjumbosuperlocussupermousesuperpioussuperscoutsupersoundsupertorussupertoughsupper-hour supper␣hoursupportfulsuppositumsupposuressuspicioussuspirioustoughens␣uptrout␣poutsturbopauseturbopumpsultrapiousuncaptiousuncouplersunderpoursunespousedunhopefulsunperilousunpollutesunpopulousunpreciousunpurposedunpurposesunspaciousunspeciousunsportfulunsproutedunspuriousunsuperiorunsupposedunvaporousupconjuresupper␣houseUpper␣Southuproariousupspoutingupsproutedup␣the␣spouturogomphusuroplaquesuser␣groupsusucapionsusucaptionusucaptorsusurpationusurpatoryvituperousvoluptuous

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